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Ibruxen 140 mg (Ibrutinib)

The manufacturer identified for Ibruxen 140 mg is Everest Pharmaceuticals Ltd. Everest’s product database lists Ibruxen as Ibrutinib INN 140 mg.

Manufacturer and product relationship

RoleEntity
Ibruxen manufacturerEverest Pharmaceuticals Ltd.
Ibruxen active ingredientIbrutinib
Ibruxen strength140 mg
Ibruxen dosage formCapsule
Reference brandIMBRUVICA
Reference-product developmentPharmacyclics/Janssen collaboration

Who developed ibrutinib?

The development history of ibrutinib is associated with Pharmacyclics and Janssen. Janssen described IMBRUVICA as jointly developed and commercialized by Janssen and Pharmacyclics.

Pharmacyclics later became an AbbVie company, while Janssen continued its collaboration and commercialization role.

Manufacturer versus originator

These roles should not be confused.

A manufacturer makes a specific pharmaceutical product.

An originator/developer is associated with the development of the active pharmaceutical ingredient and/or original reference medicine.

A brand owner owns a particular commercial brand.

A marketing authorization holder is legally responsible for a medicinal product authorization in a particular jurisdiction.

A distributor handles supply and distribution.

These roles can belong to different organizations.

Quality information

Specific manufacturing-site, batch-release, GMP-certification or authorization details should be verified against current Everest Pharmaceuticals documentation and applicable regulatory records rather than assumed from the existence of the product.